Amazon’s New Supplement Testing Requirements: What Sellers Need to Do Now
[Updated Sept 22 2025: Amazon has added Joint Health Supplements to its category of higher-risk products that require the additional testing through their recognized labs]
Key takeaway:
Amazon is rolling out a third-party testing program for dietary supplements, beginning with high-risk categories (weight loss, sexual health, bodybuilding/sports nutrition). Sellers will be prompted via email to submit product information and lab results through an Amazon portal. Testing is to be coordinated with one of Amazon’s currently recognized labs (Eurofins, UL, or NSF), though prior results from reputable ISO 17025–accredited labs may still be considered. Brands should review specifications with manufacturers now to avoid suppression.
Introduction
Amazon is tightening listing requirements for dietary supplements. Historically, most sellers provided a manufacturer’s GMP certification and a certificate of analysis (COA). Under the new approach, Amazon will require test results routed through a limited set of recognized labs, with workflows handled via an Amazon portal once a seller receives a notice. Because operational details and timing are still evolving, brands should treat this as a priority readiness project—especially those in high-risk categories.
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Who Is Affected First
Amazon is prioritizing products in:
Weight loss
Sexual health
Bodybuilding / sports nutrition
Products such as multivitamins or fish oils may not be immediately affected, but expansion to additional categories is possible. Sellers will be notified by Amazon if/when their products are pulled into scope.
How the New Testing Flow Works (High Level)
Amazon notification:
Sellers receive an email notice that testing is required for specific ASINs.Portal intake:
Within Amazon’s portal, the seller selects a recognized lab, identifies the product, uploads the label, and provides ingredient/spec info.Lab engagement & quotes:
The chosen lab acts as the coordinator—confirming what needs to be tested, establishing methods, quotes, timelines, and any needed clarifications. Sellers are responsible for costs.Prior data review (possible):
If a brand has recent test results from a reputable ISO/IEC 17025–accredited lab or robust in-house/manufacturer COAs, the recognized lab can review those and decide whether additional testing is still required.Final determination:
The recognized lab reports results back to Amazon via the portal. Outcomes may include continued listing or suppression if requirements are not met.
Currently recognized labs (per Amazon communications): Eurofins, UL (Underwriters Laboratories), and NSF.
Immediate Actions for Brands (Do These Now)
1) Pull and review product specifications
Confirm that finished product specifications are complete and defensible, not just raw material specs.
Ensure method suitability and acceptance criteria are defined (identity, potency, microbes, heavy metals, relevant adulterants).
Verify you can produce recent manufacturer COAs aligned to those specs.
2) Talk to your manufacturer
Confirm they understand Amazon’s direction and whether they can support with timely data and retained samples.
Ask whether their internal lab is ISO/IEC 17025–accredited; if not, confirm which third-party lab(s) they use and the accreditation status.
Align on turnaround times, sample pulls, and retest policies.
3) Map your lab strategy
Identify a primary recognized lab (Eurofins, UL, NSF) for each affected product.
If you already use a strong ISO 17025–accredited lab (not on the recognized list), package previous results for review and gap-analysis (what remains to be tested, if anything).
4) Prepare for backlog
Expect high volumes at recognized labs during rollout.
Assign an internal point person to monitor timelines, escalate delays, and keep Amazon deadlines visible.
Build a calendar buffer; even perfect submissions can slip due to lab queue times.
5) Update internal SOPs
Add an “Amazon testing” decision node to your quality/compliance workflow (when notified → portal intake → lab selection → sample logistics → review → submission).
Clarify owner roles (Regulatory, QA, Ops) and handoffs.
What If Your Prior COAs Are From a Non-Recognized Lab?
Recognized labs may review credible data from other ISO 17025–accredited labs and determine whether additional testing is required. Brands relying on non-accredited in-house results should anticipate extra testing. Regardless, gather the best available records now (methods, results, lab accreditation certificates) to streamline review.
Risk Areas to Watch
Lab capacity & communication: Expect slower response times. Keep escalation contacts handy.
Method suitability & matrix effects: Some ingredients or delivery systems (e.g., certain botanicals or complex blends) need specialized methods. Be prepared to justify methods or perform method verification.
Spec gaps: “Meets GMP” is not enough. Amazon’s recognized labs will look for clear pass/fail criteria.
Deadlines & suppression risk: Even compliant products can be late if labs are backlogged. Track due dates and document delays.
Readiness Checklist (Grab-and-Go)
Finished product specifications (potency, identity, micro, contaminants)
Current COAs (finished product + critical raw materials)
Lab accreditation letters (ISO/IEC 17025)
Method write-ups / validation summaries (as applicable)
Internal SOP addendum for Amazon testing workflow
Escalation contacts at chosen lab(s)
Calendar with Amazon due dates and lab ETA buffers
Key Takeaways
Amazon is moving supplement listings toward recognized-lab testing, starting with high-risk categories.
Sellers will be notified and must submit through an Amazon portal, coordinating directly with a recognized lab.
Prior ISO 17025 results may help, but additional testing can still be required.
Get ahead by tightening specs, aligning with your manufacturer, and planning for lab backlogs.
Update SOPs so the process is repeatable as Amazon expands categories.
FAQ
Do all supplements on Amazon need new third-party testing right now?
Not immediately. Rollout is prioritized for weight loss, sexual health, and bodybuilding/sports nutrition. Additional categories may follow; Amazon will notify sellers.
Which labs are recognized by Amazon?
Eurofins, UL (Underwriters Laboratories), and NSF are currently recognized. Amazon may expand the list over time.
Will Amazon accept my existing COAs?
Recognized labs can review existing results—especially from ISO/IEC 17025–accredited labs—and decide whether more testing is needed.
Who pays for testing?
Sellers are responsible for costs arranged with the recognized lab.
Can delays at the lab cause suppression?
If results are not submitted by Amazon’s due date, suppression is possible—even if the delay was outside your control. Build buffers and escalate early.
Calls-to-Action
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About Blue Ocean Regulatory
Blue Ocean Regulatory helps supplement and functional food brands launch and scale compliantly. Core specialties include FDA/FTC label & claims review, substantiation dossiers, cGMP programs, manufacturer vetting, test & stability strategies, and retailer/investor readiness. Our goal: build brands that last—and pass.